- 1919: The National Bank of South Africa becomes a correspondent of Guaranty Trust Company, providing Guaranty Trust clients with credit information and data relating to foreign trade conditions and opportunities in South Africa.
- 1959: Chase Manhattan Bank establishes a wholly-owned subsidiary, The Chase Manhattan Bank (South Africa) Ltd. Offices open in Johannesburg and Cape Town.
- 1961: The Chase Manhattan Bank (South Africa) Ltd. opens a second office in Johannesburg, which becomes the new head office. The following year it opens an office in Durban.
- 1979: Morgan Guaranty Trust Company makes a US$11 million loan for use by the Urban Foundation, a South African non-profit focused on financing housing for Black South Africans.
- 1994: J.P. Morgan leads a group of institutional investors on a tour of South Africa to provide them with a firsthand look at opportunities for investing in public debt, equity, and private placement issues by the new South Africa government, private and state-owned companies, and nongovernment development agencies.
- 1994: Robert Fleming & Co. enters a joint venture with Martin & Co., a South African company, to form Fleming Martin Securities Ltd.
- 1995: Chase Manhattan Bank reopens a representative office in Johannesburg.
- 1995: J.P. Morgan introduces the J.P. Morgan South Africa Bond Index, the first index to track the market for the liquid rand-denominated South African bonds.
- 1997: J.P. Morgan opens a representative office in Johannesburg.
- 2003: J.P. Morgan leads Telkom SA, a South African telecommunications company, in their initial public equity offering. This is the first public equity offering of a state-owned asset by the government of South Africa.
- 2007: JPMorgan Chase announces a commitment of US$1 billion worth of lending facilities or financial instruments to help cities fund building retrofit projects as part of the Energy Efficiency Building Retrofit Program. Johannesburg is one of 16 cities selected to participate.
- 2021: J.P. Morgan launches a US$20 million fund for Black-owned businesses in South Africa. Over eight years the firm aims to support 500 early-stage businesses and generate a minimum of 1,000 new permanent jobs, creating US$1.2 billion of financing in the South African economy.